- Argentina is regarded as one of the most dynamic wine-producing nations in the world, and possibly the most important wine-producing region in South America. Only four countries in the world produce more wine than Argentina. Considerable investments (much of which has come from famous French, Italian and California wine producers) have been made in new vineyards and winemaking technology in the past several years, which along with recent plantings of more premium varieties of grapes, has made Argentina much more competitive internationally. The Mendoza region is the most important region in Argentina's wine industry. And Malbec, among other Bordeaux varietals grown here, reigns supreme. Click for a list of bestselling items from Argentina.